PRF fibrin

Our body possesses natural, immense regenerative abilities. It continuously carries out ongoing repairs, ensuring that we remain healthy and in good condition. Our internal, incredibly complex cell regeneration system is responsible for this work. Today, regenerative medicine successfully utilizes this knowledge in many fields.

Thanks to the remarkable potential provided by cell biostimulation and the body's natural regenerative capacity, platelet-rich fibrin is widely employed in dentistry, supporting various procedures. This includes dental surgery, periodontology, and implantology, among others.

What is platelet-rich fibrin? 

Platelet-rich fibrin (PRF), professionally known as Platelet Rich Fibrin, is a next-generation platelet concentrate obtained from the patient's own blood. It naturally stimulates faster tissue regeneration, soft tissue healing, and bone reconstruction. It contains a range of factors that accelerate the formation of new blood vessels (angiogenesis) and the creation of new cells, thus activating the body for rapid regeneration.

It is precisely the highly concentrated platelets, proteins, and growth factors within platelet-rich fibrin that are responsible for the healing and tissue regeneration process.

The key lies in the special three-dimensional structure of platelet-rich fibrin. Thanks to this structure, platelets are more effectively stimulated to release growth factors, proteins (cytokines), and the movement of mesenchymal stem cells to the site of bodily damage, facilitating a quick repair process.

How does it work? A simple procedure at Luxdentica

The procedure involves collecting blood from the patient, then depending on the type of fraction we want to obtain, spinning the blood in a specialized centrifuge according to a precisely defined protocol, and then administering the platelet-rich fibrin to the patient. The simplified procedure allows for the treatment to be performed during a single visit to the dental office. Each procedure consists of 3 stages.

• Blood collection: 5 minutes
• Blood spinning: 5-15 minutes
• Platelet-rich fibrin administration: 5-20 minutes

Platelet-rich fibrin is obtained from the patient's own blood, which eliminates the risk of intolerance, immunological reactions, and viral infections. During the procedure, appropriate sterility procedures must be followed.

Effects of using platelet-rich fibrin:

• Accelerated healing process of periodontal tissues and diseased areas in the oral cavity.
• Maintenance of tissue structures around the tooth socket after tooth extraction.
• Accelerated tissue regeneration around inserted implants.
• Reconstruction of soft tissues.
• Reconstruction of bone defects.
• Reduction of pain symptoms.
• Natural dressing that accelerates healing and regeneration.

Worth knowing more

Platelet-rich fibrin exists in two forms: the liquid fraction I-PRF and the advanced fraction A-PRF.

A-PRF dent is an advanced fraction of platelet-rich fibrin, which in its gelatinous mass form is used to create natural dressings in the form of:

• membranes - applied directly to areas around implants to accelerate tissue regeneration after implant insertion.
• plugs - used to fill extraction sockets to expedite socket healing and reduce pain after tooth extraction.

I-PRF dent is a liquid fraction of platelet-rich fibrin with a high concentration of platelets and leukocytes, releasing growth factors and retaining mesenchymal stem cells in its spaces. Due to its liquid form, it can be easily introduced into hard-to-reach places with a needle.

• When combined with bone substitute materials, I-PRF dent creates a dense, flexible material for forming bone grafts.